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Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage
The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors. However, some functional proteins in erythroid precursors are lost during the development of red blood cells...
Autores principales: | Stolwijk, Jeffrey M., Stefely, Jonathan A., Veling, Mike T., van ‘t Erve, Thomas J., Wagner, Brett A., Raife, Thomas J., Buettner, Garry R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322435/ https://www.ncbi.nlm.nih.gov/pubmed/34298465 http://dx.doi.org/10.1016/j.redox.2021.102073 |
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