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Differentiation of human pluripotent stem cells into functional airway basal stem cells

Airway basal cells play an essential role in the maintenance of the airway epithelium. Here, we provide a detailed directed differentiation protocol to generate ‘‘induced basal cells (iBCs)’’ from human pluripotent stem cells. iBCs recapitulate biological and functional properties of airway basal ce...

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Detalles Bibliográficos
Autores principales: Suzuki, Shingo, Hawkins, Finn J., Barillà, Cristina, Beermann, Mary Lou, Kotton, Darrell N., Davis, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322461/
https://www.ncbi.nlm.nih.gov/pubmed/34355203
http://dx.doi.org/10.1016/j.xpro.2021.100683