Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1

Effective cancer chemotherapy treatment requires both therapy delivery and retention by malignant cells. Cancer cell overexpression of the multidrug transmembrane transporter gene ABCB1 (MDR1, multi-drug resistance protein 1) thwarts therapy retention, leading to a drug-resistant phenotype. We explo...

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Detalles Bibliográficos
Autores principales: McQuerry, Jasmine A., Chen, Jinfeng, Chang, Jeffrey T., Bild, Andrea H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322466/
https://www.ncbi.nlm.nih.gov/pubmed/34298440
http://dx.doi.org/10.1016/j.tranon.2021.101181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322466/
https://www.ncbi.nlm.nih.gov/pubmed/34298440
http://dx.doi.org/10.1016/j.tranon.2021.101181

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