Impacts of anti‐inflammatory phosphodiesterase inhibitors on a murine model of chronic pulmonary inflammation

Chronic obstructive pulmonary disease (COPD) often tends to respond poorly to glucocorticoid (GC) therapy. Reduced Histone deacetylase‐2 (HDAC‐2) activity is an important mechanism behind this GC insensitivity. In this study, we investigated the effects of three phosphodiesterase inhibitors (PDEIs),...

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Detalles Bibliográficos
Autores principales: Zheng, Xiao‐Fang, Chen, Dan‐Dan, Zhu, Xiao‐Ling, Le Grange, Jehane Michael, Zhou, Lu‐Qian, Zhang, Jin‐Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322673/
https://www.ncbi.nlm.nih.gov/pubmed/34327862
http://dx.doi.org/10.1002/prp2.840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322673/
https://www.ncbi.nlm.nih.gov/pubmed/34327862
http://dx.doi.org/10.1002/prp2.840

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