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Impacts of anti‐inflammatory phosphodiesterase inhibitors on a murine model of chronic pulmonary inflammation
Chronic obstructive pulmonary disease (COPD) often tends to respond poorly to glucocorticoid (GC) therapy. Reduced Histone deacetylase‐2 (HDAC‐2) activity is an important mechanism behind this GC insensitivity. In this study, we investigated the effects of three phosphodiesterase inhibitors (PDEIs),...
Autores principales: | Zheng, Xiao‐Fang, Chen, Dan‐Dan, Zhu, Xiao‐Ling, Le Grange, Jehane Michael, Zhou, Lu‐Qian, Zhang, Jin‐Nong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322673/ https://www.ncbi.nlm.nih.gov/pubmed/34327862 http://dx.doi.org/10.1002/prp2.840 |
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