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Dependence on Autophagy for Autoreactive Memory B Cells in the Development of Pristane-Induced Lupus

The production of autoantibodies by autoreactive B cells plays a major role in the pathogenesis of lupus. Increases in memory B cells have been observed in human lupus patients and autoimmune lpr mice. Autophagy is required for the maintenance of memory B cells against viral infections; however, whe...

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Detalles Bibliográficos
Autores principales: Jang, Albert, Sharp, Robert, Wang, Jeffrey M., Feng, Yin, Wang, Jin, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322733/
https://www.ncbi.nlm.nih.gov/pubmed/34335611
http://dx.doi.org/10.3389/fimmu.2021.701066