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Dependence on Autophagy for Autoreactive Memory B Cells in the Development of Pristane-Induced Lupus
The production of autoantibodies by autoreactive B cells plays a major role in the pathogenesis of lupus. Increases in memory B cells have been observed in human lupus patients and autoimmune lpr mice. Autophagy is required for the maintenance of memory B cells against viral infections; however, whe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322733/ https://www.ncbi.nlm.nih.gov/pubmed/34335611 http://dx.doi.org/10.3389/fimmu.2021.701066 |