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A Phase 3, Single-Arm, Prospective Study of Remestemcel-L, Ex Vivo Culture-Expanded Adult Human Mesenchymal Stromal Cells for the Treatment of Pediatric Patients Who Failed to Respond to Steroid Treatment for Acute Graft-versus-Host Disease

Steroid-refractory acute graft-versus-host disease (SR-aGVHD) following hematopoietic cell transplantation (HSCT) is associated with poor clinical outcomes. Currently, there are no safe and effective therapies approved for use in the pediatric population under the age of 12 years. Accordingly, there...

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Detalles Bibliográficos
Autores principales: Kurtzberg, Joanne, Abdel-Azim, Hisham, Carpenter, Paul, Chaudhury, Sonali, Horn, Biljana, Mahadeo, Kris, Nemecek, Eneida, Neudorf, Steven, Prasad, Vinod, Prockop, Susan, Quigg, Troy, Satwani, Prakash, Cheng, Annie, Burke, Elizabeth, Hayes, Jack, Skerrett, Donna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322819/
https://www.ncbi.nlm.nih.gov/pubmed/32018062
http://dx.doi.org/10.1016/j.bbmt.2020.01.018