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A Phase 3, Single-Arm, Prospective Study of Remestemcel-L, Ex Vivo Culture-Expanded Adult Human Mesenchymal Stromal Cells for the Treatment of Pediatric Patients Who Failed to Respond to Steroid Treatment for Acute Graft-versus-Host Disease
Steroid-refractory acute graft-versus-host disease (SR-aGVHD) following hematopoietic cell transplantation (HSCT) is associated with poor clinical outcomes. Currently, there are no safe and effective therapies approved for use in the pediatric population under the age of 12 years. Accordingly, there...
Autores principales: | Kurtzberg, Joanne, Abdel-Azim, Hisham, Carpenter, Paul, Chaudhury, Sonali, Horn, Biljana, Mahadeo, Kris, Nemecek, Eneida, Neudorf, Steven, Prasad, Vinod, Prockop, Susan, Quigg, Troy, Satwani, Prakash, Cheng, Annie, Burke, Elizabeth, Hayes, Jack, Skerrett, Donna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322819/ https://www.ncbi.nlm.nih.gov/pubmed/32018062 http://dx.doi.org/10.1016/j.bbmt.2020.01.018 |
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