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Bayesian Physics-Based Modeling of Tau Propagation in Alzheimer's Disease

Amyloid-β and hyperphosphorylated tau protein are known drivers of neuropathology in Alzheimer's disease. Tau in particular spreads in the brains of patients following a spatiotemporal pattern that is highly sterotypical and correlated with subsequent neurodegeneration. Novel medical imaging te...

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Detalles Bibliográficos
Autores principales: Schäfer, Amelie, Peirlinck, Mathias, Linka, Kevin, Kuhl, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322942/
https://www.ncbi.nlm.nih.gov/pubmed/34335308
http://dx.doi.org/10.3389/fphys.2021.702975