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Efficacy and safety of anti-CD45–saporin as conditioning agent for RAG deficiency
BACKGROUND: Mutations in the recombinase-activating genes cause severe immunodeficiency, with a spectrum of phenotypes ranging from severe combined immunodeficiency to immune dysregulation. Hematopoietic stem cell transplantation is the only curative option, but a high risk of graft failure and poor...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322962/ https://www.ncbi.nlm.nih.gov/pubmed/32387109 http://dx.doi.org/10.1016/j.jaci.2020.04.033 |