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Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals

The RNA-binding protein tristetraprolin (TTP) is an anti-inflammatory factor that prompts the mRNA decay of target mRNAs and is involved in inflammatory diseases such as rheumatoid arthritis (RA). TTP is regulated by phosphorylation, and protein phosphatase 2A (PP2A) can dephosphorylate TTP to activ...

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Detalles Bibliográficos
Autores principales: lv, Linxi, Qin, Ting, Huang, Qiushi, Jiang, Hui, Chen, Feng, Long, Fan, Ren, Long, Liu, Jianpin, Xie, Yongen, Zeng, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322984/
https://www.ncbi.nlm.nih.gov/pubmed/34335573
http://dx.doi.org/10.3389/fimmu.2021.675534