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Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals
The RNA-binding protein tristetraprolin (TTP) is an anti-inflammatory factor that prompts the mRNA decay of target mRNAs and is involved in inflammatory diseases such as rheumatoid arthritis (RA). TTP is regulated by phosphorylation, and protein phosphatase 2A (PP2A) can dephosphorylate TTP to activ...
Autores principales: | lv, Linxi, Qin, Ting, Huang, Qiushi, Jiang, Hui, Chen, Feng, Long, Fan, Ren, Long, Liu, Jianpin, Xie, Yongen, Zeng, Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322984/ https://www.ncbi.nlm.nih.gov/pubmed/34335573 http://dx.doi.org/10.3389/fimmu.2021.675534 |
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