Induction of synergistic non-apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells

Following surgery and chemoradiation, ~50% of patients with locally advanced head and neck tumors experience relapse within the first two years, with a poor prognosis. Therefore, a novel therapeutic approach is required. The aim of the present study was to investigate the effect of combination treat...

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Detalles Bibliográficos
Autores principales: Hattori, Kazuhiro, Takano, Naoharu, Kazama, Hiromi, Moriya, Shota, Miyake, Keitaro, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323012/
https://www.ncbi.nlm.nih.gov/pubmed/34345305
http://dx.doi.org/10.3892/ol.2021.12941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323012/
https://www.ncbi.nlm.nih.gov/pubmed/34345305
http://dx.doi.org/10.3892/ol.2021.12941

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