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Synthesis of Hetaryl-Substituted Asymmetric Porphyrins and Their Affinity to SARS-CoV-2 Helicase

Novel porphyrin compounds containing benzothiazole, benzoxazole, and benzimidazole moieties have been prepared and their structures have been confirmed. Molecular docking of non-symmetric hetaryl-substituted porphyrins and chlorin e6 with SARS-CoV-2 helicase has been carried out. The affinity of het...

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Detalles Bibliográficos
Autores principales: Syrbu, S. A., Kiselev, A. N., Lebedev, M. A., Gubarev, Yu. A., Yurina, E. S., Lebedeva, N. Sh.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323091/
https://www.ncbi.nlm.nih.gov/pubmed/34345157
http://dx.doi.org/10.1134/S1070363221060098