Cargando…
Unifying Catalysis Framework to Dissect Proteasomal Degradation Paradigms
[Image: see text] Diverging from traditional target inhibition, proteasomal protein degradation approaches have emerged as novel therapeutic modalities that embody distinct pharmacological profiles and can access previously undrugged targets. Small molecule degraders have the potential to catalytica...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323112/ https://www.ncbi.nlm.nih.gov/pubmed/34345664 http://dx.doi.org/10.1021/acscentsci.1c00389 |