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Metformin Affects Gut Microbiome Composition and Function and Circulating Short-Chain Fatty Acids: A Randomized Trial

OBJECTIVE: To determine the longer-term effects of metformin treatment and behavioral weight loss on gut microbiota and short-chain fatty acids (SCFAs). RESEARCH DESIGN AND METHODS: We conducted a 3-parallel-arm, randomized trial. We enrolled overweight/obese adults who had been treated for solid tu...

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Detalles Bibliográficos
Autores principales: Mueller, Noel T., Differding, Moira K., Zhang, Mingyu, Maruthur, Nisa M., Juraschek, Stephen P., Miller, Edgar R., Appel, Lawrence J., Yeh, Hsin-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323185/
https://www.ncbi.nlm.nih.gov/pubmed/34006565
http://dx.doi.org/10.2337/dc20-2257