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Novel method of real-time PCR-based screening for common fetal trisomies

BACKGROUND: The non-invasive prenatal test (NIPT) is based on next generation sequencing (NGS) and is used for screening for fetal trisomy. However, it is time-consuming and technically difficult. Recently, peptide nucleic acid (PNA) probe-based real-time polymerase chain reaction (RT-PCR) was devel...

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Detalles Bibliográficos
Autores principales: Kim, So Yeon, Lee, Seung Mi, Kim, Sun Min, Kim, Byoung Jae, Koo, Ja Nam, Oh, Ig Hwan, Oh, Sohee, Park, Chan-Wook, Jun, Jong Kwan, Lim, Ji Hyae, Ryu, Hyun Mee, Park, Joong Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323267/
https://www.ncbi.nlm.nih.gov/pubmed/34330281
http://dx.doi.org/10.1186/s12920-021-01039-1