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Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload
BACKGROUND: The skeletal muscle plays a central role in glucose homeostasis through the uptake of glucose from the extracellular medium in response to insulin. A number of factors are known to disrupt the normal response to insulin leading to the emergence of insulin resistance (IR). Advanced age an...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323306/ https://www.ncbi.nlm.nih.gov/pubmed/34330275 http://dx.doi.org/10.1186/s12915-021-01082-5 |