Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload

BACKGROUND: The skeletal muscle plays a central role in glucose homeostasis through the uptake of glucose from the extracellular medium in response to insulin. A number of factors are known to disrupt the normal response to insulin leading to the emergence of insulin resistance (IR). Advanced age an...

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Detalles Bibliográficos
Autores principales: Vieira-Lara, Marcel A., Dommerholt, Marleen B., Zhang, Wenxuan, Blankestijn, Maaike, Wolters, Justina C., Abegaz, Fentaw, Gerding, Albert, van der Veen, Ydwine T., Thomas, Rachel, van Os, Ronald P., Reijngoud, Dirk-Jan, Jonker, Johan W., Kruit, Janine K., Bakker, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323306/
https://www.ncbi.nlm.nih.gov/pubmed/34330275
http://dx.doi.org/10.1186/s12915-021-01082-5

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