Cargando…

α-Mangostin Induces Apoptosis in Human Osteosarcoma Cells Through ROS-Mediated Endoplasmic Reticulum Stress via the WNT Pathway

α-mangostin has been confirmed to promote the apoptosis of MG-63 cells, but its specific pro-apoptosis mechanism in osteosarcoma (OS) remains further investigation. Here, we demonstrated that α-mangostin restrained the viability of OS cells (143B and Saos-2), but had little effect on the growth of n...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Shengsen, Zhou, Fei, Dong, Yi, Ren, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323427/
https://www.ncbi.nlm.nih.gov/pubmed/34318699
http://dx.doi.org/10.1177/09636897211035080