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HepGentox: a novel promising HepG2 reportergene-assay for the detection of genotoxic substances in complex mixtures

BACKGROUND: In risk assessment, genotoxicity is a key factor to determine the safety for the consumer. Most in vitro genotoxicity assays were developed for the assessment of pure substances. However, in recent years more attention has been given to complex mixtures, where usually low amounts of a su...

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Detalles Bibliográficos
Autores principales: Pinter, Elisabeth, Friedl, Christina, Irnesberger, Alexandra, Czerny, Thomas, Piwonka, Tina, Peñarroya, Alfonso, Tacker, Manfred, Riegel, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323594/
https://www.ncbi.nlm.nih.gov/pubmed/34395098
http://dx.doi.org/10.7717/peerj.11883