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Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases

For most antimicrobial compounds with intracellular targets, getting inside the cell is the major obstacle limiting their activity. To pass this barrier some antibiotics mimic the compounds of specific interest for the microbe (siderophores, peptides, carbohydrates, etc.) and hijack the transport sy...

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Detalles Bibliográficos
Autores principales: Travin, Dmitrii Y., Severinov, Konstantin, Dubiley, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323819/
https://www.ncbi.nlm.nih.gov/pubmed/34382000
http://dx.doi.org/10.1039/d0cb00208a