Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapy

More than half of cancer patients are treated with radiotherapy, which kills tumor cells by directly and indirectly inducing DNA damage, including cytotoxic DNA double-strand breaks (DSBs). Tumor cells respond to these threats by activating a complex signaling network termed the DNA damage response...

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Detalles Bibliográficos
Autores principales: Nickoloff, Jac A., Taylor, Lynn, Sharma, Neelam, Kato, Takamitsu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323830/
https://www.ncbi.nlm.nih.gov/pubmed/34337349
http://dx.doi.org/10.20517/cdr.2020.89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323830/
https://www.ncbi.nlm.nih.gov/pubmed/34337349
http://dx.doi.org/10.20517/cdr.2020.89

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