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Identification of Key Candidate Genes Related to Inflammatory Osteolysis Associated with Vitamin E-Blended UHMWPE Debris of Orthopedic Implants by Integrated Bioinformatics Analysis and Experimental Confirmation

PURPOSE: This study aims to identify differentially expressed genes (DEGs) in macrophages exposed to ultra-high-molecular-weight polyethylene (UHMWPE) or vitamin E-blended UHMWPE (VE-UHMWPE) particles, thereby providing potential targets for the treatment of inflammatory osteolysis. METHODS: The GSE...

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Detalles Bibliográficos
Autores principales: Liu, Fanxiao, Dong, Jun, Zhou, Dongsheng, Zhang, Qingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323865/
https://www.ncbi.nlm.nih.gov/pubmed/34345178
http://dx.doi.org/10.2147/JIR.S320839