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Acetate sensing by GPR43 alarms neutrophils and protects from severe sepsis

Bacterial sepsis is a major cause of mortality resulting from inadequate immune responses to systemic infection. Effective immunomodulatory approaches are urgently needed but it has remained elusive, which targets might be suitable for intervention. Increased expression of the G-protein-coupled rece...

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Detalles Bibliográficos
Autores principales: Schlatterer, Katja, Beck, Christian, Schoppmeier, Ulrich, Peschel, Andreas, Kretschmer, Dorothee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324776/
https://www.ncbi.nlm.nih.gov/pubmed/34330996
http://dx.doi.org/10.1038/s42003-021-02427-0