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Acetate sensing by GPR43 alarms neutrophils and protects from severe sepsis
Bacterial sepsis is a major cause of mortality resulting from inadequate immune responses to systemic infection. Effective immunomodulatory approaches are urgently needed but it has remained elusive, which targets might be suitable for intervention. Increased expression of the G-protein-coupled rece...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324776/ https://www.ncbi.nlm.nih.gov/pubmed/34330996 http://dx.doi.org/10.1038/s42003-021-02427-0 |