DEPDC1B regulates the progression of human chordoma through UBE2T-mediated ubiquitination of BIRC5

Chordoma is a rare bone malignancy with a high rate of local recurrence and distant metastasis. Although DEP domain-containing protein 1B (DEPDC1B) is implicated in a variety of malignancies, its relationship with chordoma is unclear. In this study, the biological role and molecular mechanism of DEP...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Tang, Liang, Xu, Ruijun, Ma, Junpeng, Tian, Kaibing, Liu, Yanbin, Lu, Yanghu, Wu, Zhen, Zhu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324777/
https://www.ncbi.nlm.nih.gov/pubmed/34330893
http://dx.doi.org/10.1038/s41419-021-04026-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324777/
https://www.ncbi.nlm.nih.gov/pubmed/34330893
http://dx.doi.org/10.1038/s41419-021-04026-7

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