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DEPDC1B regulates the progression of human chordoma through UBE2T-mediated ubiquitination of BIRC5
Chordoma is a rare bone malignancy with a high rate of local recurrence and distant metastasis. Although DEP domain-containing protein 1B (DEPDC1B) is implicated in a variety of malignancies, its relationship with chordoma is unclear. In this study, the biological role and molecular mechanism of DEP...
Autores principales: | Wang, Liang, Tang, Liang, Xu, Ruijun, Ma, Junpeng, Tian, Kaibing, Liu, Yanbin, Lu, Yanghu, Wu, Zhen, Zhu, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324777/ https://www.ncbi.nlm.nih.gov/pubmed/34330893 http://dx.doi.org/10.1038/s41419-021-04026-7 |
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