Tailoring the effect of antithrombin-targeting therapy in haemophilia A using in silico thrombin generation

Factor (F) VIII deficiency causes bleeding in haemophilia A patients because of the reduced formation of procoagulant enzyme thrombin, which is needed to make the blood clot. We measured the dynamics of coagulation in haemophilia A patients by measuring thrombin generation (TG). Additionally, we qua...

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Detalles Bibliográficos
Autores principales: de Laat-Kremers, Romy M. W., Ninivaggi, Marisa, van Moort, Iris, de Maat, Moniek, de Laat, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324778/
https://www.ncbi.nlm.nih.gov/pubmed/34330995
http://dx.doi.org/10.1038/s41598-021-95066-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324778/
https://www.ncbi.nlm.nih.gov/pubmed/34330995
http://dx.doi.org/10.1038/s41598-021-95066-8

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