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Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI

Acute kidney injury (AKI) is associated with significant morbidity and its chronic inflammation contributes to subsequent chronic kidney disease (CKD) development. Yes-associated protein (YAP), the major transcriptional coactivator of the Hippo pathway, has been shown associated with chronic inflamm...

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Detalles Bibliográficos
Autores principales: Zheng, Zhihuang, Li, Chuanlei, Shao, Guangze, Li, Jinqing, Xu, Kexin, Zhao, Zhonghua, Zhang, Zhigang, Liu, Jun, Wu, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324794/
https://www.ncbi.nlm.nih.gov/pubmed/34330891
http://dx.doi.org/10.1038/s41419-021-04041-8