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Telomere associated gene expression as well as TERT protein level and telomerase activity are altered in the ovarian follicles of aged mice
Telomeres cap the ends of eukaryotic chromosomes to maintain genomic stability and integrity during an organism’s lifespan. The length of telomeres inevitably shortens due to DNA replication, genotoxic agents, and biological aging. A limited number of cell types, e.g., stem cells, germline cells, an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324818/ https://www.ncbi.nlm.nih.gov/pubmed/34330985 http://dx.doi.org/10.1038/s41598-021-95239-5 |