Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway

Transient receptor potential vanilloid 4 (TRPV4) plays an important role in chondrocytes via Ca(2+) signaling. However, its role in the progression of osteoarthritis is unclear. This study aimed to evaluate the effects of TRPV4 activation on articular cartilage and chondrocytes stimulated with inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Hattori, Kyosuke, Takahashi, Nobunori, Terabe, Kenya, Ohashi, Yoshifumi, Kishimoto, Kenji, Yokota, Yutaka, Suzuki, Mochihito, Kojima, Toshihisa, Imagama, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324869/
https://www.ncbi.nlm.nih.gov/pubmed/34330980
http://dx.doi.org/10.1038/s41598-021-94938-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324869/
https://www.ncbi.nlm.nih.gov/pubmed/34330980
http://dx.doi.org/10.1038/s41598-021-94938-3

Ejemplares similares