Validation of nasospheroids to assay CFTR functionality and modulator responses in cystic fibrosis

The availability of a simple, robust and non-invasive in vitro airway model would be useful to study the functionality of the cystic fibrosis transmembrane regulator (CFTR) protein and to personalize modulator therapy for cystic fibrosis (CF) patients. Our aim was to validate a CFTR functional study...

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Detalles Bibliográficos
Autores principales: Calucho, Maite, Gartner, Silvia, Barranco, Paula, Fernández-Álvarez, Paula, Pérez, Raquel García, Tizzano, Eduardo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324871/
https://www.ncbi.nlm.nih.gov/pubmed/34330959
http://dx.doi.org/10.1038/s41598-021-94798-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324871/
https://www.ncbi.nlm.nih.gov/pubmed/34330959
http://dx.doi.org/10.1038/s41598-021-94798-x

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