MicroRNA-186 ameliorates Knee osteoarthritis via regulation of P2X7-mediated Cathepsin-K/Runx2/ADAMTS5 signalling axis in articular chondrocytes

Knee osteoarthritis (KOA) is a chronic joint disorder involving the articular cartilage and tissues around the synovial joint. The key objective of this study was to determine the effect of miR-186-5p administration on the expression of pathogenic signalling in the chondrocytes using a surgical dest...

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Detalles Bibliográficos
Autores principales: Deng, RuLin, Zhang, HongJun, Huang, Lei, Xiong, Xin, Fu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324999/
https://www.ncbi.nlm.nih.gov/pubmed/34354409
http://dx.doi.org/10.1016/j.sjbs.2021.06.091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324999/
https://www.ncbi.nlm.nih.gov/pubmed/34354409
http://dx.doi.org/10.1016/j.sjbs.2021.06.091

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