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Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs

Mass-spectrometry-based phosphoproteomics can identify more than 10,000 phosphorylated sites in a single experiment. But, despite the fact that enormous phosphosite information has been accumulated in public repositories, protein kinase–substrate relationships remain largely unknown. Here, we descri...

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Detalles Bibliográficos
Autores principales: Niinae, Tomoya, Imami, Koshi, Sugiyama, Naoyuki, Ishihama, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325102/
https://www.ncbi.nlm.nih.gov/pubmed/34186244
http://dx.doi.org/10.1016/j.mcpro.2021.100119