Emodin inhibits viability, proliferation and promotes apoptosis of hypoxic human pulmonary artery smooth muscle cells via targeting miR-244-5p/DEGS1 axis

OBJECTIVE: This study aimed to determine the effects of emodin on the viability, proliferation and apoptosis of human pulmonary artery smooth muscle cells (PASMCs) under hypoxia and to explore the underling molecular mechanisms. METHODS: PASMCs were cultured in a hypoxic environment (1% oxygen) and...

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Detalles Bibliográficos
Autores principales: Yi, Li, Liu, JunFang, Deng, Ming, Zuo, Huihua, Li, Mingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325255/
https://www.ncbi.nlm.nih.gov/pubmed/34332565
http://dx.doi.org/10.1186/s12890-021-01616-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325255/
https://www.ncbi.nlm.nih.gov/pubmed/34332565
http://dx.doi.org/10.1186/s12890-021-01616-1

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