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Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody

Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that have evolved resistance. In this paper, we map a fitness mo...

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Detalles Bibliográficos
Autores principales: Meijers, Matthijs, Vanshylla, Kanika, Gruell, Henning, Klein, Florian, Lässig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325275/
https://www.ncbi.nlm.nih.gov/pubmed/34301904
http://dx.doi.org/10.1073/pnas.2104651118