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Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody
Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that have evolved resistance. In this paper, we map a fitness mo...
Autores principales: | Meijers, Matthijs, Vanshylla, Kanika, Gruell, Henning, Klein, Florian, Lässig, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325275/ https://www.ncbi.nlm.nih.gov/pubmed/34301904 http://dx.doi.org/10.1073/pnas.2104651118 |
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