Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries

Germ cells form the basis for sexual reproduction by producing gametes. In ovaries, primordial germ cells exit the cell cycle and the pluripotency-associated state, differentiate into oogonia, and initiate meiosis. Despite the importance of germ cell differentiation for sexual reproduction, signalin...

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Detalles Bibliográficos
Autores principales: Le Rolle, Morgane, Massa, Filippo, Siggers, Pam, Turchi, Laurent, Loubat, Agnès, Koo, Bon-Kyoung, Clevers, Hans, Greenfield, Andy, Schedl, Andreas, Chaboissier, Marie-Christine, Chassot, Anne-Amandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325354/
https://www.ncbi.nlm.nih.gov/pubmed/34301885
http://dx.doi.org/10.1073/pnas.2023376118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325354/
https://www.ncbi.nlm.nih.gov/pubmed/34301885
http://dx.doi.org/10.1073/pnas.2023376118

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