Submicron particle docetaxel intratumoral injection in combination with anti-mCTLA-4 into 4T1-Luc orthotopic implants reduces primary tumor and metastatic pulmonary lesions

We describe here characterization of the response of local and metastatic disease and immunomodulation following intratumoral (IT) injection of submicron particle docetaxel (SPD) administered alone or in combination with systemic antibody anti-mCTLA-4 (anti-mCTLA-4) in the metastatic 4T1-Luc2-1A4 (4...

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Detalles Bibliográficos
Autores principales: Maulhardt, Holly, Marin, Alyson, Hesseltine, Holly, diZerega, Gere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325653/
https://www.ncbi.nlm.nih.gov/pubmed/34331595
http://dx.doi.org/10.1007/s12032-021-01555-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325653/
https://www.ncbi.nlm.nih.gov/pubmed/34331595
http://dx.doi.org/10.1007/s12032-021-01555-1

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