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FBXO16-mediated hnRNPL ubiquitination and degradation plays a tumor suppressor role in ovarian cancer
Heterogeneous nuclear ribonucleoprotein L (hnRNPL) is a type of RNA binding protein that highly expressed in a variety of tumors and plays a vital role in tumor progression. However, its post-translational regulation through ubiquitin-mediated proteolysis and the cellular mechanism responsible for i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325689/ https://www.ncbi.nlm.nih.gov/pubmed/34333526 http://dx.doi.org/10.1038/s41419-021-04040-9 |