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Key residues of Bacillus thuringiensis Cry2Ab for oligomerization and pore-formation activity

As a pore-forming toxin, activation, oligomerization and pore-formation were both required for the mode of action of Cry toxins. Previous results revealed that the helices α4–α5 of Domain I were involved in the oligomerization of Cry2Ab, however, the key residues for Cry2Ab aggregation remained ambi...

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Detalles Bibliográficos
Autores principales: Pan, Zhi-Zhen, Xu, Lian, Liu, Bo, Chen, Qing-Xi, Zhu, Yu-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325727/
https://www.ncbi.nlm.nih.gov/pubmed/34331618
http://dx.doi.org/10.1186/s13568-021-01270-0