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Pressure-induced changes on the morphology and gene expression in mammalian cells

We evaluated the effect of high hydrostatic pressure on mouse embryonic fibroblasts (MEFs) and mouse embryonic stem (ES) cells. Hydrostatic pressures of 15, 30, 60, and 90 MPa were applied for 10 min, and changes in gene expression were evaluated. Among genes related to mechanical stimuli, death-ass...

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Detalles Bibliográficos
Autores principales: Okamoto, Kazuko, Watanabe, Tomonobu M., Horie, Masanobu, Nishiyama, Masayoshi, Harada, Yoshie, Fujita, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325925/
https://www.ncbi.nlm.nih.gov/pubmed/34258610
http://dx.doi.org/10.1242/bio.058544