Chimeric human opsins as optogenetic light sensitisers

Human opsin-based photopigments have great potential as light-sensitisers, but their requirement for phototransduction cascade-specific second messenger proteins may restrict their functionality in non-native cell types. In this study, eight chimeric human opsins were generated consisting of a backb...

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Detalles Bibliográficos
Autores principales: Hickey, Doron G., Davies, Wayne I. L., Hughes, Steven, Rodgers, Jessica, Thavanesan, Navamayooran, MacLaren, Robert E., Hankins, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325934/
https://www.ncbi.nlm.nih.gov/pubmed/34151984
http://dx.doi.org/10.1242/jeb.240580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325934/
https://www.ncbi.nlm.nih.gov/pubmed/34151984
http://dx.doi.org/10.1242/jeb.240580

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