Cargando…
Chimeric human opsins as optogenetic light sensitisers
Human opsin-based photopigments have great potential as light-sensitisers, but their requirement for phototransduction cascade-specific second messenger proteins may restrict their functionality in non-native cell types. In this study, eight chimeric human opsins were generated consisting of a backb...
Autores principales: | Hickey, Doron G., Davies, Wayne I. L., Hughes, Steven, Rodgers, Jessica, Thavanesan, Navamayooran, MacLaren, Robert E., Hankins, Mark W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325934/ https://www.ncbi.nlm.nih.gov/pubmed/34151984 http://dx.doi.org/10.1242/jeb.240580 |
Ejemplares similares
-
ON-bipolar cell gene expression during retinal degeneration: Implications for optogenetic visual restoration
por: Gilhooley, Michael J., et al.
Publicado: (2021) -
Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways
por: Hughes, Steven, et al.
Publicado: (2016) -
Using a bistable animal opsin for switchable and scalable optogenetic inhibition of neurons
por: Rodgers, Jessica, et al.
Publicado: (2021) -
The Oesophageal Cancer Multidisciplinary Team: Can Machine Learning Assist Decision-Making?
por: Thavanesan, Navamayooran, et al.
Publicado: (2023) -
Optogenetic strategies for high-efficiency all-optical interrogation using blue-light-sensitive opsins
por: Forli, Angelo, et al.
Publicado: (2021)