Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9

In adaptive immunity, CLEC-2(+) dendritic cells (DCs) contact fibroblastic reticular cells (FRCs) inhibiting podoplanin-dependent actomyosin contractility, permitting FRC spreading and lymph node expansion. The molecular mechanisms controlling lymph node remodelling are incompletely understood. We a...

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Detalles Bibliográficos
Autores principales: de Winde, Charlotte M., Makris, Spyridon, Millward, Lindsey J., Cantoral-Rebordinos, Jesús A., Benjamin, Agnesska C., Martínez, Víctor G., Acton, Sophie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325952/
https://www.ncbi.nlm.nih.gov/pubmed/34184727
http://dx.doi.org/10.1242/jcs.258610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325952/
https://www.ncbi.nlm.nih.gov/pubmed/34184727
http://dx.doi.org/10.1242/jcs.258610

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