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Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9
In adaptive immunity, CLEC-2(+) dendritic cells (DCs) contact fibroblastic reticular cells (FRCs) inhibiting podoplanin-dependent actomyosin contractility, permitting FRC spreading and lymph node expansion. The molecular mechanisms controlling lymph node remodelling are incompletely understood. We a...
Autores principales: | de Winde, Charlotte M., Makris, Spyridon, Millward, Lindsey J., Cantoral-Rebordinos, Jesús A., Benjamin, Agnesska C., Martínez, Víctor G., Acton, Sophie E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325952/ https://www.ncbi.nlm.nih.gov/pubmed/34184727 http://dx.doi.org/10.1242/jcs.258610 |
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