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Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation

Polo kinase (PLK1 in mammals) is a master cell cycle regulator that is recruited to various subcellular structures, often by its polo-box domain (PBD), which binds to phosphorylated S-pS/pT motifs. Polo/PLK1 kinases have multiple functions at centrioles and centrosomes, and we have previously shown...

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Detalles Bibliográficos
Autores principales: Alvarez-Rodrigo, Ines, Wainman, Alan, Saurya, Saroj, Raff, Jordan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325959/
https://www.ncbi.nlm.nih.gov/pubmed/34156068
http://dx.doi.org/10.1242/jcs.258987