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Characterization of β-adrenergic receptors in bovine intramuscular and subcutaneous adipose tissue: comparison of lubabegron fumarate with β-adrenergic receptor agonists and antagonists

Chinese hamster ovary cell constructs expressing either the β (1)-, β (2)- or β (3)-adrenergic receptor (AR) were used to determine whether a novel β-AR modulator, lubabegron fumarate (LUB; Experior, Elanco Animal Health) might exert greater potency for a specific β-AR subtype. EC(50) values calcula...

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Detalles Bibliográficos
Autores principales: Hwang, Jinhee H, Spurlock, Michael E, Kube, John C, Li, Xiang Z, Smith, Stephen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326056/
https://www.ncbi.nlm.nih.gov/pubmed/34337647
http://dx.doi.org/10.1093/jas/skab116