Crystal structure of the MyRF ICA domain with its upstream β-helical stalk reveals the molecular mechanisms underlying its trimerization and self-cleavage

Myelin gene regulatory factor (MyRF), a novel membrane transcription factor expressed on the endoplasmic reticulum membrane, functions as a trimer. The trimerization of MyRF is associated with a fragment between the DNA binding domain and transmembrane domain that shares homology with the triple-β-h...

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Detalles Bibliográficos
Autores principales: Wu, Pei, Zhen, Xiangkai, Li, Bowen, Yu, Qian, Huang, Xiaochen, Shi, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326128/
https://www.ncbi.nlm.nih.gov/pubmed/34345217
http://dx.doi.org/10.7150/ijbs.57673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326128/
https://www.ncbi.nlm.nih.gov/pubmed/34345217
http://dx.doi.org/10.7150/ijbs.57673

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