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Targeting ITK signaling for T cell-mediated diseases

The focus of this review is to examine the role of ITK signaling in multiple diseases and investigate the clinical potential of ITK inhibition. The diseases and potential interventions reviewed include T cell-derived malignancies as well as other neoplastic diseases, allergic diseases such as asthma...

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Detalles Bibliográficos
Autores principales: Weeks, Samuel, Harris, Rebecca, Karimi, Mobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326193/
https://www.ncbi.nlm.nih.gov/pubmed/34368657
http://dx.doi.org/10.1016/j.isci.2021.102842